One HETLIOZ® 20 mg capsule per day*
Clinical effect on sleep cycles requires an adequate trial of up to several (eg, 3) months of daily use with HETLIOZ®, due to the nature and variance of circadian rhythms.1,2
*Not actual size.
References: 1. HETLIOZ® [prescribing information]. Vanda Pharmaceuticals Inc. 2014. 2. Lockley SW, et al. Lancet. 2015;386(10005):1754-1764.
The most common adverse reactions (incidence >5% and at least twice as high on HETLIOZ® (tasimelteon) than on placebo) were headache, increased alanine aminotransferase, nightmares or unusual dreams, and upper respiratory or urinary tract infection. The risk of adverse reactions may be greater in elderly (>65 years) patients than younger patients because exposure to HETLIOZ® is increased by approximately 2-fold compared with younger patients.
HETLIOZ® is indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (Non-24).
Please see full Prescribing Information.